Southern Illinois Vacation Packages

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Photo by Southernmost Illinois Tourism Bureau

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Your Southern Illinois Vacation

When adventure is calling, answer it with a vacation package to Southern Illinois. Well known for its culture and history, this is one destination you'll never forget. Start your trip to Southern Illinois with a few nights in O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Effingham is another city that draws travellers from far and wide. Lake Sara and Effingham Performance Centre are two of the leading places to see in this destination. Quit dreaming and get packing, because your Southern Illinois vacation is just clicks away with Expedia.

Top Southern Illinois Vacation Deals

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was CA $1,462, price is now CA $1,061 per person
CA $1,061
per person
Aug 6 - Aug 9
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
9.2/10 Wonderful! (1,667 reviews)
Very clean & pleasant staff. Breakfast had a very good selection even though they say it is Continental style.

Reviewed on Jun 24, 2026

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
Midtown
Price was CA $1,666, price is now CA $1,249 per person
CA $1,249
per person
Jul 29 - Aug 3
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
7.8/10 Good! (1,002 reviews)
Suite was well stocked with utensils etc. The room was clean. Staff was nice. Pool was small and our bathroom door in our room didn’t latch, which was tough with 2 toddlers waddling about.

Reviewed on May 20, 2026

The Cheshire

The Cheshire

4 out of 5
Price was CA $1,761, price is now CA $1,407 per person
CA $1,407
per person
Jul 29 - Aug 3
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
8.8/10 Excellent! (1,000 reviews)
Hi-Point best neighborhood, near the park

Reviewed on Jun 16, 2026

Landing Amazing 1bd, Yoga Studio, Gym

Landing Amazing 1bd, Yoga Studio, Gym

3 out of 5
DeBaliviere Place
Price was CA $2,115, price is now CA $1,700 per person
CA $1,700
per person
Jul 29 - Aug 3
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
No reviews
Moonrise Hotel

Moonrise Hotel

4 out of 5
Delmar Loop
Price was CA $1,620, price is now CA $1,309 per person
CA $1,309
per person
Jul 29 - Aug 3
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
9/10 Wonderful! (1,981 reviews)
Great hotel, on the Loop, staff is always helpful. On-site parking. Nice little workout room. Restaurant. Coffee shops and food nearby.

Reviewed on Jun 25, 2026

Where to stay in Southern Illinois

Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
Aerial view of the iconic Gateway Arch and Mississippi River with urban skyline and bridges, Downtown St. Louis, Missouri, United States.

Eastport

1 out of top 10 points of interest in this area

If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.

Find hotels in Eastport

Ready to book your vacation to Southern Illinois?

 

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Southern Illinois Hotel Deals

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
The price is CA $141 per night from Jul 19 to Jul 20
CA $141
CA $159 total
Jul 19 - Jul 20
includes taxes & fees
9.2/10 Wonderful! (1,000 reviews)
"The property was very clean! Staff was friendly, very professional and prompt. Rooms were very clean and well maintained. Pool and gym were nice! Continental breakfast remained fully stocked until 9:30a.m. with a great selection of food items."

Reviewed on Jun 23, 2026

Drury Inn & Suites St. Louis Fairview Heights
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.5 out of 5
145 North 44th Street  Mount Vernon IL
Fully refundableReserve now, pay when you stay
The price is CA $185 per night from Jun 28 to Jun 29
CA $185
CA $208 total
Jun 28 - Jun 29
includes taxes & fees
9.6/10 Exceptional! (1,705 reviews)
"Great breakfast and dinner"

Reviewed on Jun 24, 2026

Drury Plaza Hotel Mt. Vernon
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

2 out of 5
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
The price is CA $87 per night from Jul 12 to Jul 13
CA $87
CA $100 total
Jul 12 - Jul 13
includes taxes & fees
6.6/10 (1,014 reviews)
"Bed bugs need I say more."

Reviewed on Jun 24, 2026

Super 8 by Wyndham O'Fallon
See all 1,136 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Southern Illinois

Superman Statue

Superman Statue

Superman fans will love getting a photograph taken in front of this giant statue of the Man of Steel himself, dressed in his iconic red-and-blue guise.

Superman Statue
Beautiful landscape of Lake Shelbyville, Illinois during sunset

Lake Shelbyville Beach

Why not spend a carefree afternoon at Lake Shelbyville Beach during your travels in Shelbyville? While you're in the area, wander around the forests.

Lake Shelbyville Beach

DuQuoin State Fairgrounds

Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.

DuQuoin State Fairgrounds

Frequently asked questions

Can I cancel my flight booking to Southern Illinois due to COVID-19?
If you haven't booked yet, check the terms and conditions of your preferred carrier. If you've already locked in your flight to Southern Illinois, click through to our Customer Service Portal. The information here will help determine which COVID-19 policies apply to your booking and advise the next steps.
What's the best way to find cheap flights to Southern Illinois that have flexible change policies?
At Expedia, we've been channeling our inner gymnast to bring you the most flexible fares around. Just click on "No change fee" under the filter heading "Flexible change policies" to find your perfect flight to Southern Illinois.
What are some of the general tips for travelers to Southern Illinois during the COVID-19 outbreak?
With new COVID-19 rules and measures to adhere to, travel looks a bit different at present. Here are some useful things to know before you hop on that plane to Southern Illinois:
  • Research the rules and restrictions in both your origin and destination. You may not be able to travel depending on local circumstances, so make sure you check before you lock in your flight.
  • Wear a face mask during airport screening. A TSA employee will ask you to temporarily lower your mask for ID purposes.
  • To minimize the risk of cross-contamination, place your boarding pass on the scanner yourself and then hold it up for inspection. Do not hand your pass directly to a TSA officer.
  • One liquid hand sanitizer container is now allowed in your carry-on baggage. It must be no larger than 12 oz (350 ml), and you'll need to take it out of your bag for X-ray scanning.
  • To reduce handling during the screening process, place items such as your phone, keys and wallet into your carry-on rather than the bins.
  • Transport your food items in a clear plastic bag and also put them in a screening bin. Keeping your food separate from your carry-on makes it less likely that a TSA agent will need to open your bag for inspection.

Which airlines fly to Southern Illinois?
Cape Air is a well-known carrier servicing Southern Illinois. Search for a ticket to Williamson County Regional Airport (MWA) and you'll have 160 Cape Air flights a month to pick from.
How can I find cheap tickets to Southern Illinois?
A useful strategy for scoring cheap tickets is to be flexible with your travel dates. Begin with searching for your flight to Southern Illinois, then click on the "flexible dates" box to compare prices for nearby days. Want another tip? Book in advance. To give you an idea of costs, was the lowest price for a flight to Southern Illinois in the last seven days.
How much is a flight to Southern Illinois?
In the last seven days, round-trip tickets to Southern Illinois sold for as low as and reached a maximum of . For one-way trips taking off from (), the lowest amount paid during this same period was .
What are the most popular airports to fly into in Southern Illinois?
The main gateway to Southern Illinois, about 160 flights cruise into Williamson County Regional Airport (MWA) each month. Keep an eye out for a rewarding deal, lock in your seat and get set to discover this sensational region.
When is the cheapest time to fly to Southern Illinois?
If you'd rather spend your vacation savings enjoying Southern Illinois rather than on your trip there, jet off earlier in the week. The most economical day to travel is usually Tuesday, with Monday close behind. With many folks keeping their travel to weekends, Saturday tends to have the most expensive airfares.
How much is a plane ticket to Southern Illinois?
In the last seven days, plane tickets varied between and . Check out our sensational deals to Southern Illinois, make a booking and then get ready for your getaway!
Which airlines with flights to Southern Illinois employ COVID-19 cleanliness policies?
In response to the global COVID-19 pandemic, airlines have implemented additional actions and measures to help their passengers get back in the air. Here are some great examples:
  • Southwest Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.