Southern Illinois Vacation Packages
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Your Southern Illinois Vacation
When adventure is calling, answer it with a vacation package to Southern Illinois. Well known for its culture and history, this is one destination you'll never forget. Start your trip to Southern Illinois with a few nights in O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Effingham is another city that draws travellers from far and wide. Lake Sara and Effingham Performance Centre are two of the leading places to see in this destination. Quit dreaming and get packing, because your Southern Illinois vacation is just clicks away with Expedia.
Top Southern Illinois Vacation Deals
Price found within the past 48 hours. Click for updated prices.
The West End
Central West End
CA $1,424
per person
Oct 31 - Nov 3
found 22 hours ago
Roundtrip flight included
Grande Prairie (YQU) to St. Louis (STL)
8.6/10 Excellent! (629 reviews)
Check in parking terrible. Overprice for what is offered. Nothing included in room price. Very inconvenient for handicapped accessible. No ice other then going to front desk or bar. Shower head leaking so sprayed everywhere. Will not recommend.
Reviewed on Sep 23, 2026
The Wildwood Hotel
CA $1,466
per person
Oct 31 - Nov 3
found 22 hours ago
Roundtrip flight included
Grande Prairie (YQU) to St. Louis (STL)
9.2/10 Wonderful! (1,657 reviews)
Very nice hotel. Only concern is the single elevator, since the front desk is on a different level than the bulk of the rooms. Makes for congestion in the morning when housecleaning staff are using it.
Reviewed on Sep 23, 2026
SpringHill Suites by Marriott St. Louis Chesterfield
CA $1,465
per person
Oct 31 - Nov 3
found 22 hours ago
Roundtrip flight included
Grande Prairie (YQU) to St. Louis (STL)
9.2/10 Wonderful! (40 reviews)
Beautiful new hotel! The welcoming staff at the SpringHill Suites St. Louis Chesterfield made us feel right at home immediately. The property is spotless and modern, and the wonderful breakfast was the perfect bonus! 10/10 stay!
Reviewed on Sep 21, 2026
Where to stay in Southern Illinois
Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
Eastport
If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.
Mulberry Hills
While Mulberry Hills isn't home to many top sights, World's Largest Catsup Bottle and Kruta Bakery are some notable places to visit nearby.
Uptown
If you're spending some time in Uptown, Kruta Bakery and World's Largest Catsup Bottle are top sights worth seeing.
Alorton
Alorton is well-liked for its restaurants. If you'd like to do some sightseeing in the greater East St. Louis area, you might plan a trip to Frank Holten State Recreation Area or Arsenal BG Ballpark.
Historic Downtown Collinsville
While Historic Downtown Collinsville isn't home to many top sights, World's Largest Catsup Bottle and Kruta Bakery are some notable places to visit nearby.
Ready to book your vacation to Southern Illinois?
Southern Illinois Hotel Deals
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
CA $131
CA $148 total
Sep 28 - Sep 29
includes taxes & fees
Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
CA $135
CA $162 total
Oct 18 - Oct 19
includes taxes & fees
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
CA $156
CA $176 total
Oct 4 - Oct 5
includes taxes & fees
9.8/10 Exceptional! (1,813 reviews)
"Great place"
Reviewed on Sep 23, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Southern Illinois attractions
Garden of the Gods Recreation Area
9.8/10 (63 reviews)
See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
World Wide Technology Raceway
9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
O'Fallon Family Sports Park
8.6/10 (137 reviews)
Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Check out the shops and top-notch restaurants in this family-friendly area.
Frequently asked questions
How much does a Southern Illinois vacation package cost?
From just CA $1,424, you can tailor make your Southern Illinois vacation package. Simply bundle hotels, flights and car rentals and be rewarded with discounts.
How do I get a cheap travel package to Southern Illinois?
Bundle your flights and hotels with Expedia to save big on your next big adventure. With over 550 airlines and 1,000,000 hotels globally, your Southern Illinois vacation package can be tailored exactly to suit your budget. With all that extra money, why not throw in one or more awesome activities and tours? It's an easy way to unlock even more discounts. Your dream getaway to Southern Illinois is much closer than you thought!
What are the top hotels in Southern Illinois?
Take a look at Super 8 by Wyndham Carbondale and Best Western Saluki Inn. They're top picks for lots of travelers to Carbondale. If Marion is on your travel itinerary, Super 8 by Wyndham Marion and Quality Inn And Suites are a couple of popular options.
How far in advance should I book my Southern Illinois vacation?
Reward yourself with the widest variety at the lowest prices by booking your vacation to Southern Illinois early. Air carriers usually sell flight tickets around 12 months before departure, so reserve your spot ASAP. That said, Expedia is dedicated to giving you the best bargains around, so it's never a bad time to book your dream vacation!
What does an Expedia Southern Illinois travel package include?
That depends on what sort of trip you're contemplating. Southern Illinois vacation deals can include flights, hotels and car rentals. You can mix and match to create the travel package that suits you. You can also add on experiences and activities after you've booked to get even bigger discounts.
What should I know before booking a Southern Illinois travel package?
You'll score excellent savings when you combine your flights, hotels and rental cars into a package. Not only that, booking everything in one spot will make your trip planning easier. So why waste your money or time? Whether you're organizing a ritzy city getaway or a low-cost family road trip, explore our vacation packages today.
Can I choose my airline with a Southern Illinois Expedia vacation package?
You can, and with more than 550 airlines to pick from across the globe, you're not short on choice. Browse the available options and see which airline fits your needs and budget.
If I'm not able to travel, can I cancel my Southern Illinois vacation package?
You can cancel your Southern Illinois booking if your plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.
Explore a world of travel with Expedia
- Cozy Lake of Egypt Cabin & Pond
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- Guest Houses in Dowell
- Keyesport Hotels
- Hotel Wedding Venues Hotels in Southern Illinois
- Adults Only Resorts & in Southern Illinois
- Pet-Friendly Hotels in Mount Vernon
- Marion Hotels
- B&B in Patoka
- Vacation Homes in Corinth
- Hunter's Retreat
- Holiday Inn Express & Suites Salem by IHG
- Cabin Rentals in Waltonville
- Du Quoin Hotels
- B&B in Centralia
- Super 8 by Wyndham Du Quoin
- Drury Inn & Suites Marion
- B&B in Du Quoin
- Hotels near Franklin County Fairgrounds
- Lgbt Friendly Hotels in Mount Vernon
- Motels in Carlyle
- Villas in Galatia
- Cabin Rentals in Salem
- Hotels with Balconies in Marion
- Best location on Lake of Egypt by land and by water!
- Cabin Rentals in Omaha
- Mount Erie Hotels
- Modern Pond
- 3 Star Hotels in Royalton
- Johnston City Hotels
- Tamaroa Hotels
- Hotels with a Pool in Southern Illinois
- Washington County Hotels
- Holiday Inn Express & Suites Mount Vernon by IHG
- Galatia Hotels
- Benton Hotels
- America's Best Inns Hotels in Waltonville
- Resorts in Harrisburg
- Farmstay in Dowell
- Cottages in Zeigler
- Eldorado Hotels
- Super 8 by Wyndham Salem
- Belle Prairie City Hotels
- Farmstay in Sunfield
- Hotels with smoking rooms in Marion
- Carmi Hotels
- Hotels with Hot Tubs in Carlyle
- Mcleansboro Hotels
- Hotels with an Indoor Pool in Harrisburg
- Keenes Hotels
- Rv Parks in Cutler
- Thompsonville Hotels
- Villas in Benton
- Apartments in Cisne
- Harrisburg Hotels
- Quality Inn & Suites Marion
- Villas in Buckner
- 3 Star Hotels in Keenes
- Cabin Rentals in Carlyle
- Best Western Plus Centralia Hotel & Suites
- Mount Vernon Hotels
- Treehouse w/ Hot Tub near Shawnee National Forest
- Apartments in Fairfield
- Flights from Toronto (YYZ) to Carbondale (MDH)
- Flights from Vancouver (YVR) to Mount Vernon (MVN)
- Flights to Ina
- Flights from Benton
- Flights to Fairfield
- Flights from Waltonville
- Flights from Carterville
- Flights from Mount Vernon
- Flights from Belle Rive
- Flights to Marion
- Flights to Centralia
- Flights to Southern Illinois
- Flights from Cutler
- Flights from Cisne
- Flights from Macedonia
- Flights to Benton
- Flights from Elkville
- Flights from Christopher
- Flights from Phoenix (PHX) to Carbondale (MDH)
- Flights to Du Quoin
- Flights from Cleveland (CLE) to Carbondale (MDH)
- Flights to Patoka
- Flights to Mount Vernon
- Flights to Flora
- Flights from Ewing
- Flights from Columbus (CMH) to Carbondale (MDH)
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
