Southern Illinois Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

Photo by Southernmost Illinois Tourism Bureau

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Southern Illinois Vacation

When adventure is calling, answer it with a vacation package to Southern Illinois. Well known for its culture and history, this is one destination you'll never forget. Start your trip to Southern Illinois with a few nights in O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Effingham is another city that draws travellers from far and wide. Lake Sara and Effingham Performance Centre are two of the leading places to see in this destination. Quit dreaming and get packing, because your Southern Illinois vacation is just clicks away with Expedia.

Top Southern Illinois Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG

3.5 out of 5
Price was CA $970, price is now CA $910 per person
CA $910
per person
Dec 18 - Dec 20
found 17 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
7.6/10 Good! (1,001 reviews)
It was clean and have no complaints.

Reviewed on Nov 3, 2026

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was CA $1,284, price is now CA $1,000 per person
CA $1,000
per person
Dec 18 - Dec 20
found 17 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
9.2/10 Wonderful! (1,677 reviews)
Everything was good. Seemed that the property was not full but we were forced into a suite.

Reviewed on Nov 7, 2026

The Respite Bed and Breakfast

The Respite Bed and Breakfast

4.5 out of 5
Price was CA $1,502, price is now CA $1,419 per person
CA $1,419
per person
Jan 8 - Jan 12
found 1 day ago
Roundtrip flight included
Calgary (YYC) to Paducah (PAH)
9.8/10 Exceptional! (370 reviews)
We had some problems at first with getting in the building and getting upstairs (we're in our seventies, and have bad knees), but they were mostly just a lack of experience on our part. The place was clean and quiet, and the breakfast in the morning was good.

Reviewed on Nov 5, 2026

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

2.5 out of 5
Price was CA $992, price is now CA $954 per person
CA $954
per person
Dec 18 - Dec 20
found 17 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
8.2/10 Very good! (1,005 reviews)

Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield

3 out of 5
Price was CA $1,033, price is now CA $997 per person
CA $997
per person
Dec 18 - Dec 20
found 17 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
9.6/10 Exceptional! (1,008 reviews)

Where to stay in Southern Illinois

Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
An aerial view of a city with a prominent river, a large bridge, and surrounding buildings.

Eastport

If you're spending some time in Eastport, Splash City Family Waterpark and Gateway Conference Center are top sights worth seeing.

Find hotels in Eastport

Ready to book your vacation to Southern Illinois?

 

Choose your dates

Southern Illinois Hotel Deals

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.5 out of 5
145 North 44th Street  Mount Vernon IL
Fully refundableReserve now, pay when you stay
The price is CA $157 per night from Nov 15 to Nov 16
CA $157
CA $177 total
Nov 15 - Nov 16
includes taxes & fees
Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
The price is CA $127 per night from Nov 15 to Nov 16
CA $127
CA $144 total
Nov 15 - Nov 16
includes taxes & fees
Drury Inn & Suites St. Louis Fairview Heights
Baymont by Wyndham Effingham

Baymont by Wyndham Effingham

2.5 out of 5
1811 W Fayette Avenue Effingham IL
Fully refundableReserve now, pay when you stay
The price is CA $108 per night from Nov 14 to Nov 15
CA $108
CA $120 total
Nov 14 - Nov 15
includes taxes & fees
Baymont by Wyndham Effingham
See all 1,224 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

9.8/10 (63 reviews)
See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
See properties

Frequently asked questions

How much does a Southern Illinois vacation package cost?
From just CA $910, you can tailor make your Southern Illinois vacation package. Simply bundle hotels, flights and car rentals and be rewarded with discounts.
How do I get a cheap travel package to Southern Illinois?
Bundle your flights and hotels with Expedia to save big on your next big adventure. With over 550 airlines and 1,000,000 hotels globally, your Southern Illinois vacation package can be tailored exactly to suit your budget. With all that extra money, why not throw in one or more awesome activities and tours? It's an easy way to unlock even more discounts. Your dream getaway to Southern Illinois is much closer than you thought!
What are the top hotels in Southern Illinois?
Take a look at Super 8 by Wyndham Carbondale and Best Western Saluki Inn. They're top picks for lots of travelers to Carbondale. If Marion is on your travel itinerary, Super 8 by Wyndham Marion and Quality Inn And Suites are a couple of popular options.
How far in advance should I book my Southern Illinois vacation?
Reward yourself with the widest variety at the lowest prices by booking your vacation to Southern Illinois early. Air carriers usually sell flight tickets around 12 months before departure, so reserve your spot ASAP. That said, Expedia is dedicated to giving you the best bargains around, so it's never a bad time to book your dream vacation!
What does an Expedia Southern Illinois travel package include?
That depends on what sort of trip you're contemplating. Southern Illinois vacation deals can include flights, hotels and car rentals. You can mix and match to create the travel package that suits you. You can also add on experiences and activities after you've booked to get even bigger discounts.
What should I know before booking a Southern Illinois travel package?
You'll score excellent savings when you combine your flights, hotels and rental cars into a package. Not only that, booking everything in one spot will make your trip planning easier. So why waste your money or time? Whether you're organizing a ritzy city getaway or a low-cost family road trip, explore our vacation packages today.
Can I choose my airline with a Southern Illinois Expedia vacation package?
You can, and with more than 550 airlines to pick from across the globe, you're not short on choice. Browse the available options and see which airline fits your needs and budget.
If I'm not able to travel, can I cancel my Southern Illinois vacation package?
You can cancel your Southern Illinois booking if your plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.