Southern Illinois Vacation Packages
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Your Southern Illinois Vacation
When adventure is calling, answer it with a vacation package to Southern Illinois. Well known for its culture and history, this is one destination you'll never forget. Start your trip to Southern Illinois with a few nights in O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Effingham is another city that draws travellers from far and wide. Lake Sara and Effingham Performance Centre are two of the leading places to see in this destination. Quit dreaming and get packing, because your Southern Illinois vacation is just clicks away with Expedia.
Top Southern Illinois Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Clayton Plaza Hotel & Extended Stay
Clayton
CA $862
per person
Sep 18 - Sep 21
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
9/10 Wonderful! (3,298 reviews)
The room dated and we found it to be below standards for cleanliness. The safe and the tv did not work. The bed was fine the bathroom was nice with good lighting. The business office computer/printer did not work. Parking was inconvenient but free. Staff was friendly
Reviewed on Aug 9, 2026
Where to stay in Southern Illinois
Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
Eastport
If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.
Uptown
If you're spending some time in Uptown, World's Largest Catsup Bottle and Kruta Bakery are top sights worth seeing.
Alorton
Alorton is well-liked for its restaurants. If you'd like to do some sightseeing in the greater East St. Louis area, you might plan a trip to Arsenal BG Ballpark or Gateway Arch.
Mulberry Hills
While Mulberry Hills isn't home to many top sights, World's Largest Catsup Bottle and Gateway Conference Center are some notable places to visit nearby.
Historic Downtown Collinsville
While Historic Downtown Collinsville isn't home to many top sights, World's Largest Catsup Bottle and Gateway Conference Center are some notable places to visit nearby.
Ready to book your vacation to Southern Illinois?
Southern Illinois Hotel Deals
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
CA $125
CA $142 total
Aug 16 - Aug 17
includes taxes & fees
9.2/10 Wonderful! (1,025 reviews)
"I usually have a OK experience at the Drury Inn in Fairview Heights however, last night I entered it into the room. It was very musty and smelly. I went to the front desk. All she got out was Febreze. She told me all the rooms were booked and so I asked her could I just get a room for tomorrow And ..."
Reviewed on Aug 8, 2026
Best Western St. Louis Fairview Heights
150 Ludwig Dr Fairview Heights IL
CA $111
CA $126 total
Aug 16 - Aug 17
includes taxes & fees
Baymont by Wyndham Effingham
1811 W Fayette Avenue Effingham IL
Fully refundableReserve now, pay when you stay
CA $101
CA $112 total
Aug 17 - Aug 18
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Southern Illinois attractions
Garden of the Gods Recreation Area
9.8/10 (63 reviews)
See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
O'Fallon Family Sports Park
8.6/10 (137 reviews)
Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Check out the shops and top-notch restaurants in this family-friendly area.
World Wide Technology Raceway
9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
Frequently asked questions
How much does a Southern Illinois vacation package cost?
From just CA $862, you can tailor make your Southern Illinois vacation package. Simply bundle hotels, flights and car rentals and be rewarded with discounts.
How do I get a cheap travel package to Southern Illinois?
Bundle your flights and hotels with Expedia to save big on your next big adventure. With over 550 airlines and 1,000,000 hotels globally, your Southern Illinois vacation package can be tailored exactly to suit your budget. With all that extra money, why not throw in one or more awesome activities and tours? It's an easy way to unlock even more discounts. Your dream getaway to Southern Illinois is much closer than you thought!
What are the top hotels in Southern Illinois?
Take a look at Super 8 by Wyndham Carbondale and Best Western Saluki Inn. They're top picks for lots of travelers to Carbondale. If Marion is on your travel itinerary, Super 8 by Wyndham Marion and Quality Inn And Suites are a couple of popular options.
How far in advance should I book my Southern Illinois vacation?
Reward yourself with the widest variety at the lowest prices by booking your vacation to Southern Illinois early. Air carriers usually sell flight tickets around 12 months before departure, so reserve your spot ASAP. That said, Expedia is dedicated to giving you the best bargains around, so it's never a bad time to book your dream vacation!
What does an Expedia Southern Illinois travel package include?
That depends on what sort of trip you're contemplating. Southern Illinois vacation deals can include flights, hotels and car rentals. You can mix and match to create the travel package that suits you. You can also add on experiences and activities after you've booked to get even bigger discounts.
What should I know before booking a Southern Illinois travel package?
You'll score excellent savings when you combine your flights, hotels and rental cars into a package. Not only that, booking everything in one spot will make your trip planning easier. So why waste your money or time? Whether you're organizing a ritzy city getaway or a low-cost family road trip, explore our vacation packages today.
Can I choose my airline with a Southern Illinois Expedia vacation package?
You can, and with more than 550 airlines to pick from across the globe, you're not short on choice. Browse the available options and see which airline fits your needs and budget.
If I'm not able to travel, can I cancel my Southern Illinois vacation package?
You can cancel your Southern Illinois booking if your plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.
Explore a world of travel with Expedia
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- Flights from Toronto (YYZ) to Carbondale (MDH)
- Flights from Vancouver (YVR) to Mount Vernon (MVN)
- Flights to Ina
- Flights from Benton
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- Flights to Southern Illinois
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- Flights to Du Quoin
- Flights from Cleveland (CLE) to Carbondale (MDH)
- Flights to Patoka
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- Flights from Columbus (CMH) to Carbondale (MDH)
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
